Chan Zhang

Contact Details

Email: zhangchan@th.btbu.edu.cn

Telephone/Mobile (optional):

Office: 010-68984547

Education Background

Sept. 2007-Jun. 2012: University Name: China Agricultural University. Degree and Major: PhD., Microbiology

Sept. 2003-Jun. 2007: University Name:  Dalian University. Degree and Major:  Bachelor, Bioengineering.

Research Field/Interests

Food microbial technology and safety research, food microbial fermentation research, functional microbial metabolism and regulation research.

Research Grants

1. Beijing Nova Program, The Study of molecular mechanism of PKS genes cluster regulating monacolin K synthesis in Monascus, 2018/01-2020/12, chair.

2. Support Project of High-level Teachers in Beijing Municipal Universities in the Period of 13th Five–year Plan, Study on Key Genes of Secondary Metabolite Synthesis and Its Regulation Mechanism in Monascus, 2018/01-2020/12, chair.

3. Beijing Natural Science Foundation, Study on regulatory mechanism of Monacolin K gene cluster in Monascus based on functional genomics, 2018/01-2020/12, chair.

4. National Natural Science Foundation of China, Based on the transcriptional level to analyze metabolic pathway among Red Pigment、Monocolin K and citrinin in Monascus pilosus, 2014/01-2016/12, chair.

5. National Natural Science Foundation of China, Molecular Mechanisms of Monascus Pigment Biosynthesis in Monascus purpureus Based on Proteomics, 2015/01-2017/12, participate.

Publications

1. Jun Lv, Gao-Fei Qian, Lei Chen, Huan Liu, Hai-Xiao Xu, Gan-Rong Xu, Bo-Bo Zhang*, and Chan Zhang*. Efficient biosynthesis of natural yellow pigments by Monascus purpureus in a novel integrated fermentation system. Journal of Agricultural and Food Chemistry, 2018, 66(4): 918-925.

2. Jun Lv, Bo-Bo Zhang*, Xiao-Dong Liu, Chan Zhang, Lei Chen, Gan-Rong Xu, Peter Chi Keung Cheung. Enhanced production of natural yellow pigments from Monascus purpureus by liquid culture: The relationship between fermentation conditions and mycelial morphology. Journal of Bioscience and Bioengineering, 2017, 124(4): 452-458.

3. Chan Zhang, Jian Liang, Le Yang, Baoguo Sun, Chengtao Wang*. De Novo RNA sequencing and transcriptome analysis of Monascus purpureus and analysis of key genes involved in Monacolin K biosynthesis. PLoS One, 2017, 12(1): e0170149.

4. Chan Zhang, Jian Liang, Le Yang, Shiyuan Chai, Chenxi Zhang, Baoguo Sun, Chengtao Wang*. Glutamic acid promotes monacolin K production and monacolin K biosynthetic gene cluster expression in Monascus. AMB Express, 2017 , 7 (1): 22.

5. Lang Tiandan, Liang Jian, Wang Chengtao, Zhang Chan*, Liu Luxiang. Using high-energy hybrid particle field mutation breeding high yield Monacolin K and low yield citrinin of Monascus strains. Science and Technology of Food Industry. 2016, 37(2): 165-169.

6. Qi Tiantian, Zhang Chan*，Lang Tiandan, Wang Chengtao*, Wen Yanjun. Monascus Mutant Strains with High MonacolinK Yield Obtained by Atmospheric and Room Temperature Plasmas. Food Science. 2015, 36(9):66-70.

7. Jiachan Zhang, Chan Zhang, Lei Zhao, Chengtao Wang*. Lipase-catalyzed synthesis of sucrose fatty acid ester and the mechanism of ultrasonic promoting esterification reaction in non-aqueous media. Advanced Materials Research, 2014, 881-883: 35-41.

8. Chan Zhang, Qian Yang, Hualin Zhang, Chengtao Wang*. Optimization for Ultrasonic-Assisted on Extraction of Monascus Red Pigment and Yellow Pigments. Journal of Food Science and Biotechnology, 2014, 33(8), 805-813.

9. Chan Zhang#, Xia Meng#, Ningxiao Li, Wei Wang, Yuan Sun, Wei Jiang, Guohua Guan and Ying Li*, Two Bifunctional Enzymes with Ferric Reduction Ability Play Complementary Roles during Magnetosomes Synthesis in Magnetospirillum gryphiswaldense MSR-1. Journal of Bacteriology,2013, 195(4):876-885.

10. Chengbo Rong, Chan Zhang, Yiting Zhang , Lei Qi, Jing Yang, Ying Li*, Jilun Li, FeoB2 functions in magnetosome formation and oxidative stress protection in Magnetospirillum gryphiswaldense strain MSR-1, Journal of Bacteriology, 2012 ,194(15):3972-3976.

Teaching Interests

Food Microbiology, Animal and Plant Inspection and Quarantine, Progress in Food Safety Testing Technology